BACKGROUND: It has been suggested that magnesium can be used to reduce seru
m calcium levels seen with hyperparathyroidism during pregnancy, thus reduc
ing maternal and fetal risk.
CASE: A young woman presented at 32 weeks' gestation with abdominal pain fr
om pancreatitis caused by hyperparathyroidism. from a parathyroid adenoma.
She was started on magnesium sulfate tocolysis for preterm labor. During tr
eatment, serum parathyroid hormone was undetectable, but serum calcium and
vitamin D-1,25 were elevated. When magnesium was discontinued, her vitamin.
D-1,25 was suppressed and the parathyroid hormone was elevated.
CONCLUSION: For some patients, because of persistent hypercalcemia, magnesi
um sulfate might not be a viable treatment option for hyperparathyroidism d
uring pregnancy. (Obstet Gynecol 2001;98:923-5. (C) 2001 by the American Co
llege of Obstetricians and Gynecologists.).