IN-VITRO ANTIFUNGAL ACTIVITY OF PNEUMOCANDIN L-743,872 AGAINST A VARIETY OF CLINICALLY IMPORTANT MOLDS

Authors
DELPOETA M SCHELL WA PERFECT JR
Citation
M. Delpoeta et al., IN-VITRO ANTIFUNGAL ACTIVITY OF PNEUMOCANDIN L-743,872 AGAINST A VARIETY OF CLINICALLY IMPORTANT MOLDS, Antimicrobial agents and chemotherapy, 41(8), 1997, pp. 1835-1836
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
41
Issue
8
Year of publication
1997
Pages
1835 - 1836
Database
ISI
SICI code
0066-4804(1997)41:8<1835:IAAOPL>2.0.ZU;2-C
Abstract
The in vitro activity of the new antifungal drug pneumocandin L-743,87 2 against 55 isolates of clinically important molds was examined by an adapted macrobroth dilution method for yeasts. Pneumocandin L-743,872 exhibited in vitro antifungal activity against Alternaria sp., Asperg illus flavus, Aspergillus fumigatus, Curvularia lunata, Exophiala jean selmei, Fonsecaea pedrosoi, Paecilomyces variotii, and Scedosporium ap iospermum. The drug appeared to lack significant in vitro inhibitory a ctivity against Fusarium oxysporum, Fusarium solani, Rhizopus arrhizus , Paecilomyces lilacinus, and Scedosporium prolificans.