Recent reports suggest that selective serotonin reuptake inhibitors (SSRIs)
are useful in the treatment of individuals with autism and other pervasive
developmental disorders. We report on a single case study of the use of fl
uvoxamine with a 7-year-old Caucasian girl with severe pervasive developmen
tal disorder. Our findings indicate that fluvoxamine was significantly effe
ctive in reducing stereotypical, repetitive behaviors, anxiety, and aggress
ion and in improving prelinguistic and social behaviors. Our results indica
te that the use of the SSRIs as a platform for the longterm habilitation of
these children should be considered, but further studies are required to e
stablish the efficiency of fluvoxamine for the treatment of children with a
utism.