Reactions of the OH adducts of cytosine and its derivatives with TEMPO andTEMPOL: A steady state gamma-radiolysis and pulse radiolysis study

Authors
Chabita, K Mandal, PC Mahal, HS Mukherjee, T
Citation
K. Chabita et al., Reactions of the OH adducts of cytosine and its derivatives with TEMPO andTEMPOL: A steady state gamma-radiolysis and pulse radiolysis study, RES CHEM IN, 27(6), 2001, pp. 579-593
Citations number
25
Categorie Soggetti
Chemistry
Journal title
RESEARCH ON CHEMICAL INTERMEDIATES
ISSN journal
09226168 → ACNP
Volume
27
Issue
6
Year of publication
2001
Pages
579 - 593
Database
ISI
SICI code
0922-6168(2001)27:6<579:ROTOAO>2.0.ZU;2-E
Abstract
The reactions of the OH adducts of cytosine and its derivatives with nitrox ides namely TEMPO and TEMPOL have been followed by steady state gamma -radi olysis and pulse radiolysis. Pulse radiolysis studies show that the transie nt OH adducts of cytosine and its derivatives react with TEMPO and TEMPOL b y electron transfer reaction and not by adduct formation as was observed in the case of thymine. The second order rate constants for these electron tr ansfer reactions are of the order of 10(7) - 10(8) dm(3) mol(-1) s(-1).