A new HLA-Cw allele (Cw*1510), identified in a French Caucasian individual

Authors
Tamouza, R Schaeffer, V Marzais, F Poirier, JC Fortier, C Ramasawmy, R Sghiri, R Krishnamoorthy, R Toubert, A Charron, D
Citation
R. Tamouza et al., A new HLA-Cw allele (Cw*1510), identified in a French Caucasian individual, TISSUE ANTI, 58(2), 2001, pp. 107-108
Citations number
6
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
TISSUE ANTIGENS
ISSN journal
00012815 → ACNP
Volume
58
Issue
2
Year of publication
2001
Pages
107 - 108
Database
ISI
SICI code
0001-2815(200108)58:2<107:ANHA(I>2.0.ZU;2-L
Abstract
A novel HLA-Cw*15 allele, Cw*1510, found in a French Caucasian bone marrow recipient is described. Nucleotide sequence of the new variant is identical to the common Cw*15021 DNA sequences except nucleotides at positions 32 an d 61 of exon 2. While the first difference is silent, the second cause subs titution of an Histidine by an Arginine at amino acid position 21 of the al pha1 heavy chain domain.