Treatment of rhinocerebral mucormycosis by combination of endoscopic sinusdebridement and amphotericin B

Rhinocerebral mucormycosis (RCM) is an aggressive fungal infection vith a h igh mortality rate. It frequently develops in patients with uncontrolled di abetes mellitus or immunocompromised patients. RCM typically presents in a rapidly fulminant manner with headache, fever, mucosal necrosis, and ophtha lmic symptoms. Although the definitive diagnosis is achieved by histopathol ogical examination, computed tomography (CT) scanning and magnetic resonanc e (MR) are the best imaging procedures in early diagnosis to assess the ext ent of the disease.