The peptides of alpha-aminosuberic acid II. Synthesis of deamino-dicarba-eel-calcitonin sequence 1-9

Authors
Gut, V Cerovsky, V Zertova, M Korblova, E Malon, P Stocker, H Wunsch, E
Citation
V. Gut et al., The peptides of alpha-aminosuberic acid II. Synthesis of deamino-dicarba-eel-calcitonin sequence 1-9, AMINO ACIDS, 21(3), 2001, pp. 255-263
Citations number
14
Categorie Soggetti
Biochemistry & Biophysics
Journal title
AMINO ACIDS
ISSN journal
09394451 → ACNP
Volume
21
Issue
3
Year of publication
2001
Pages
255 - 263
Database
ISI
SICI code
0939-4451(2001)21:3<255:TPOAAI>2.0.ZU;2-D
Abstract
The paper describes the synthesis of Asu(6)-octapeptide derivatives by cond ensing two alternative pentapeptide fragments with Asu-containing tripeptid es. After partial deprotection these linear peptides compounds are subject to cyclization experiments aimed to give the N-terminal [1-9] sequence of d eamino-dicarba-eel calcitonin. This is a key substance for the semi-synthes is of the respective analogues of eel calcitonin.