Gene expression in visceral and subcutaneous adipose tissues

A large body of evidence demonstrates depot-specific differences in the exp ression of genes coding important functional proteins in adipocytes. This m ay contribute to the well-known specific functional properties of the adipo cytes from intra-abdominal and subcutaneous regions. This review will focus on the main findings regarding the regional differences in adipocyte gene expression in humans. These genes encode proteins belonging to three differ ent functional groups: the metabolic enzyme and related signalling proteins , the adipogenic factors, and, finally, the products of adipocytes.