SEROTONIN, DOPAMINE, AND MOTOR EFFECTS IN PARKINSONS-DISEASE

Authors
MIYAWAKI E MEAH Y KOLLER WC
Citation
E. Miyawaki et al., SEROTONIN, DOPAMINE, AND MOTOR EFFECTS IN PARKINSONS-DISEASE, Clinical neuropharmacology, 20(4), 1997, pp. 300-310
Citations number
102
Categorie Soggetti
Clinical Neurology","Pharmacology & Pharmacy
Journal title
Clinical neuropharmacology → ACNP
ISSN journal
03625664
Volume
20
Issue
4
Year of publication
1997
Pages
300 - 310
Database
ISI
SICI code
0362-5664(1997)20:4<300:SDAMEI>2.0.ZU;2-F
Abstract
We review recent reports suggesting that use of selective serotonergic agents that either inhibit synaptic reuptake or have specific seroton in receptor affinities may benefit a variety of motor disturbances in Parkinson's disease. The complex, mixed motoric effects of these agent s in Parkinson's disease have not allowed for a consistent view on the interrelationship between dopamine and serotonin (5HT) in motor contr ol but may speak to the nature of dysregulated neurotransmission in th e disease.