Sp. De Visser et al., Stereospecific oxidation by Compound I of Cytochrome P450 does not proceedin a concerted synchronous manner, CHEM COMMUN, (22), 2001, pp. 2322-2323
Calculations show that the transition structure for the synchronous oxygen
transfer by Compound I is a second order saddle point. The process is unlik
ely.