A new diterpene lactone from the soft coral Sarcophyton molle Tix. Dur.

Authors
Su, JY Yan, SJ Zeng, LM
Citation
Jy. Su et al., A new diterpene lactone from the soft coral Sarcophyton molle Tix. Dur., CHEM J CH U, 22(9), 2001, pp. 1515-1517
Citations number
9
Categorie Soggetti
Chemistry
Journal title
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
ISSN journal
02510790 → ACNP
Volume
22
Issue
9
Year of publication
2001
Pages
1515 - 1517
Database
ISI
SICI code
0251-0790(200109)22:9<1515:ANDLFT>2.0.ZU;2-O
Abstract
Two diterpene lactones, sarcophinone(1) and iso-sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso-Sarcophinone 2 is a new compound. Its stru cture was determined to be C-1 epimer of sarcophinone by spectroscopic meth ods. Bioassay showed that both sarcophinone(1) and iso-sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.