Assessment of the association between blood pressure control and health care resource use

Citation
P. Lapuerta et al., Assessment of the association between blood pressure control and health care resource use, CLIN THER, 23(10), 2001, pp. 1773-1782
Citations number
12
Categorie Soggetti
Pharmacology
Journal title
CLINICAL THERAPEUTICS
ISSN journal
01492918 → ACNP
Volume
23
Issue
10
Year of publication
2001
Pages
1773 - 1782
Database
ISI
SICI code
0149-2918(200110)23:10<1773:AOTABB>2.0.ZU;2-R
Abstract
Background: Several studies have reported increased health care resource us e among hypertensive patients with uncontrolled blood pressure (BP). Objective: The purpose of this study was to investigate the relationship be tween BP control and health care resource use. Methods: Data were obtained from the Caring for Hypertension on Initiation: Costs and Effectiveness (CHOICE) study, a multicenter feasibility study of actual physician and patient behavior and clinical outcomes in a naturalis tic setting. Adult patients with newly dia-nosed hypertension were randomiz ed to either Group I (treatment with diuretics or betablockers) or Group 2 (treatment with calcium channel blockers or angiotensin-converting enzyme i nhibitors) and followed for 5 +/- 1 months. Physicians practiced standard c are while documenting, medications, BP measurements, and health care resour ce use for their patients. A subsequent analysis evaluating the relationshi p between BP and physician visits was performed for the whole population an d for a subpopulation of patients with at least 4 months of follow-up data. Cox regression was used to model time to next visit. Results: A total of 512 patients with newly diagnosed hypertension were fol lowed; 399 had follow-up data for at least 4 months. Baseline demographic c haracteristics were similar in the 2 groups. Kaplan-Meier curves and a log- rank test showed that the time to next visit for patients with uncontrolled BP was significantly shorter than for patients whose BP was controlled (P < 0.05). On average, patients with uncontrolled BP (greater than or equal t o 140/90 mm Hg) had follow-up office visits similar to 13 days earlier than patients with controlled BP (< 140/90 mm Hg). This association remained si gnificant after adjustment for repeated measures, and after exclusion of th e first return visit. Cox regression analysis showed that higher systolic a nd diastolic BP measurements were significantly associated with a shorter t ime to next visit, after adjustment for age and sex. Total estimated costs during the study period were $170 per patient for medications and $283 per patient for office visits. Conclusions: In the CHOICE study, higher BP was associated with a shorter t ime to next visit. Office visits were the main cost driver in the short-ter m management of hypertension.