Clear cell papulosis (pagetoid papulosis) in a non-Asian patient

Clear cell papulosis is a recently described disorder which is characterize d by multiple flat, slightly elevated, hypopigmented papules, distributed m ainly on the lower part of the trunk of healthy children. Histologically, t he disease shows 'clear cells' with a pagetoid appearance spread among kera tinocytes in basal and suprabasal layers of the epidermis. These cells stai n for AE1, CEA and EMA, making a relationship to eccrine or apocrine elemen ts likely. All cases reported until now describe Asian children. The first European child with clear cell papulosis is presented. Copyright (C) 2001 S . Karger AG, Basel.