PURPOSE: The aim of this article was to investigate the safety, outcome, le
ngth of stay, and cost of hospital admission in patients with Crohn's disea
se who underwent laparoscopy compared with open surgery. METHODS: Among 51
consecutive patients with inflammatory bowel disease (1996-2000), 46 with C
rohn's disease were included in this nonrandomized prospective study. Of th
ese, 20 patients underwent laparoscopic surgery and 26 underwent open surge
ry. Data collected included the following information: age, gender, body ma
ss index, diagnosis, duration of disease, preoperative medical treatment, p
revious abdominal surgery, present indication for surgery, and procedure pe
rformed (comparability measures), as well as conversion to open surgery, op
erating time, time to resolution of ileus, morbidity, duration of hospital
stay, and cost of hospital admission (outcome measures). RESULTS: There was
no significant difference with respect to comparability measures between t
he laparoscopic and the open-surgery groups. There was no mortality. There
was no intraoperative complication in either group and no conversion in the
laparoscopic group, Operating time was significantly longer in the laparos
copic group (302 minutes) vs. the open group (244.7 minutes) (P < 0.05), bu
t this difference disappeared when data were adjusted for the extra time re
quired to perform the laparoscopic hand-sewn anastomoses (288.2 minutes vs.
244.7 minutes). Bowel function returned more quickly in the laparoscopic g
roup vs. the open group in terms of passage of flatus (3.7 vs. 4.77 days) (
P < 0.05) and resumption of oral intake (4.2 vs, 6.3 day) (P < 0.01). There
were significantly fewer postoperative complications in the laparoscopic g
roup (9-5 percent) vs. the open group (18.5 percent) (P < 0.05); the length
of stay was significantly shorter in the laparoscopic group (8.3 days) us.
the open group (13.2 days) (P < 0.01); and the cost of hospital admission
was significantly lower in the laparoscopic group ($6106, United States dol
lars) vs. the open group (S9829, United States dollars) (P < 0.05). CONCLUS
ION: There is a reduction in the postoperative ileus, length of stay, cost
of hospital admission, and postoperative complication rate in the laparosco
pic group. Laparoscopic surgery for Crohn's disease is safe, and it is pote
ntially more cost-effective than traditional open surgery.