Prevention of delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage

The delayed cerebral vasoconstriction known as cerebral vasospasm remains a significant cause of permanent neurological deficit and death following an eurysmal subarachnoid hemorrhage despite the best current medical therapies . The mechanism of cerebral vasospasm remains unknown. Several new drugs ha ve been tested in animal models of subarachnoid hemorrhage, and these exper imental studies have contributed to a better understanding of the potential mechanisms that lead to cerebral vasospasm. In this article, the authors h ighlight recent advances in the various treatment procedures for delayed ce rebral vasospasm following subarachnoid hemorrhage. (C) 2001 Prous Science, All rights reserved.