Y. Sugita et al., Autoimmune vesicles on the face and neck. A variant of Brunsting-Perry type localized bullous pemphigoid?, EUR J DERM, 11(6), 2001, pp. 557-559
We report a case of blistering disease presenting a unique distribution of
vesiculobullous lesions on the face and neck which is similar to Brunsting-
Perry type of localized bullous pemphigoid (BP). Histopathology of a lesion
al skin biopsy demonstrated a subepidermal blister. Direct immunofluorescen
ce demonstrated a strong linear deposition of IgG and IgA to the basement m
embrane zone, and a faint staining for C3. However, circulating antibodies
were not detected by indirect immunofluorescence and immunoblotting. And th
e patient did not develop atrophic scars and was relatively young woman. Th
is case might be a variant of Brunsting-Perry type of localized BP or local
ized epidermolysis bullosa acquisita, presenting the clinical heterogeneity
of subepidermal blistering diseases.