Inhaled nitric oxide in cardiology

Citation
Cs. Hayward et al., Inhaled nitric oxide in cardiology, EXPERT OP I, 10(11), 2001, pp. 1947-1956
Citations number
129
Categorie Soggetti
Pharmacology & Toxicology
Journal title
EXPERT OPINION ON INVESTIGATIONAL DRUGS
ISSN journal
13543784 → ACNP
Volume
10
Issue
11
Year of publication
2001
Pages
1947 - 1956
Database
ISI
SICI code
1354-3784(200111)10:11<1947:INOIC>2.0.ZU;2-I
Abstract
Inhaled nitric oxide (INO) allows selective pulmonary vasodilatation with r apidity of action. It is effective in the acute management of reversible pu lmonary hypertension in cardiac medical and surgical patients and is also u seful in assessing the pulmonary vasodilator capacity in patients with chro nic pulmonary hypertension. This review will examine the role of INO in the management of cardiac patients, compared to alternatives where available. The use of INO in cardiac failure, post-operative cardiac patients, patient s with congestive cardiac failure or congenital heart disease will also be reviewed. Newer alternatives with prolonged pulmonary activity and simpler administration are also discussed.