PERSISTENCE OF HUMAN-LEUKOCYTE ANTIGEN (HLA) ANTIBODIES AFTER ONE-YEAR IN CHILDREN RECEIVING CRYOPRESERVED VALVED ALLOGRAFTS

Authors
SHADDY RE THOMPSON DD OSBORNE KA HAWKINS JA FULLER TC
Citation
Re. Shaddy et al., PERSISTENCE OF HUMAN-LEUKOCYTE ANTIGEN (HLA) ANTIBODIES AFTER ONE-YEAR IN CHILDREN RECEIVING CRYOPRESERVED VALVED ALLOGRAFTS, The American journal of cardiology, 80(3), 1997, pp. 358
Citations number
4
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
80
Issue
3
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)80:3<358:POHA(A>2.0.ZU;2-M
Abstract
This study shows that the broad anti-HLA antibody response against cry opreserved valved allografts used for surgical repair of congenital he art disease persists beyond 1 year after implantation. In 3 patients, there were clearly defined HLA antibody specificities consistent with the HLA phenotypes of the patients, i.e., the panel-reactive antibody was directed against major alloantigen groups that were not expressed by the antibody responders.