We constructed a questionnaire to assess asthma knowledge, assessed its psy
chometric properties, and examined its association with demographic charact
eristics, psychosocial factors, and disease severity and management in 375
adults following an asthma-related emergency department visit. Overall know
ledge was poor but varied widely among respondents. Better knowledge was re
lated to younger age, higher education, and less severe disease. Chance-ori
entated health locus of control and low self-esteem were associated with lo
wer asthma knowledge. Better knowledge was associated with better disease m
anagement. We conclude that asthma education can lead to improved disease o
utcomes, and psychosocial factors need to be considered when designing inte
rventions for asthma education.