TECHNETIUM-99M-MIBI VERSUS FLUORINE-18-FDG IN DIFFUSE MULTIPLE-MYELOMA

Experience of scintigraphic detection of bone lesion and active bone m arrow involvement of multiple myeloma, especially with sestamibi and F DG-PET scans is in evolution, We report a case of intense sestamibi up take in bone marrow correlating with the extent of the disease, while FDG-PET scans showed activity only in areas of active disease progress ion associated with pain, Technetium-99m-sestamibi appears to indicate the extent of the disease, while [F-18]FDG-PET scans show sites of ac tive tumor proliferation and may be useful in directing local therapy such as radiation.