Technegas, the discrete radio-aerosol particle, containing Tc-99m has
been investigated, and the chemical evolution and physical properties
of the particle demonstrated. Methods: A commercial technegas generato
r was used to produce aerosols according to standard clinical procedur
es, The aerosols were collected by electrostatic precipitation and exa
mined with transition electron microscopy (TEM), scanning electron mic
roscopy (SEM) and force microscopy, The chemical evolution was examine
d by x-ray techniques and thermogravimetric analysis, Results: The act
ive particle was identified as hexagonal platelets of metallic technet
ium contained within a thin layer of graphitic carbon, This composite
structure is discussed in light of the metal particle behaving as a te
mplate for the carbon capsule, The average size of the observed hexago
nal platelets, 30-60 nm, was only weakly dependent on the concentratio
n of technetium in the crucible, Conclusion: The mechanism for the for
mation of the technegas particles has been developed and the particles
involved characterized. It appears that the use of other metals also
leads to the formation of similiar materials.