Effect of ramipril in a patient with glycogen storage disease type I and nephrotic-range proteinuria

Citation
I. Pela et al., Effect of ramipril in a patient with glycogen storage disease type I and nephrotic-range proteinuria, J INH MET D, 24(6), 2001, pp. 681-682
Citations number
3
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
JOURNAL OF INHERITED METABOLIC DISEASE
ISSN journal
01418955 → ACNP
Volume
24
Issue
6
Year of publication
2001
Pages
681 - 682
Database
ISI
SICI code
0141-8955(200111)24:6<681:EORIAP>2.0.ZU;2-R
Abstract
We studied the effect of ramipril on urinary protein excretion and arterial pressure in a 27-year-old patient with GSD Ia and heavy proteinuria (2-3 g /24 h). Ramipril therapy resulted in an important reduction of proteinuria (0.3-0.5 g/24 h): no changes were observed in arterial pressure and renal f unction during the 12-month follow-up. We conclude that treatment with rami pril can be employed effectively and safely in GSD Ia patients with nephrot ic-range proteinuria.