Hs. Uppal et al., Sudden onset bilateral sensorineural hearing loss: a manifestation of occult breast carcinoma, J LARYNG OT, 115(11), 2001, pp. 907-910
Diffuse infiltration of the meninges by metastatic carcinoma (meningeal car
cinomastosis) is a potential complication of systemic malignancy. It may pr
esent with a variety of neurological symptoms as any aspect of the neuraxis
can be affected. Often there is a history of pre-existing malignancy.
The authors describe a case with an initial presentation of sudden onset pr
ofound bilateral sensorineural hearing loss. The underlying pathology was f
ound to be an occult breast carcinoma, a previously unreported finding.
The role of cerebrospinal fluid cytology and radio-imaging in diagnosis is
discussed. All previously reported cases of sudden hearing loss and meninge
al carcinomatosis are reviewed.