A case of chronic. fluctuating plasma cell gingivostomatitis that progresse
d despite chemotherapy and surgery is reported. This is the first case repo
rted of treatment with radiation therapy, and one of the few cases reported
where the infiltrate has reached the larynx. After receiving low dose radi
ation therapy, via a conformal technique encompassing the respiratory mucos
al lining from the base of tongue to carina, there has been symptomatic imp
rovement.