Wb. Cammarano et al., ANESTHESIA FOR COMBINED CESAREAN-SECTION AND EXTRAADRENAL PHEOCHROMOCYTOMA RESECTION - A CASE-REPORT AND LITERATURE-REVIEW, International journal of obstetric anesthesia, 6(2), 1997, pp. 112-117
Pheochromocytoma during pregnancy is unusual, with approximately 250 c
ases now reported in the literature, The current case describes the an
esthetic management of a patient with a large extra-adrenal pheochromo
cytoma who underwent a combined cesarean section and tumor removal in
which perioperative hemodynamic control was difficult despite high-dos
e alpha-adrenergic blockade, In this case it is believed that difficul
ty in perioperative hemodynamic management was related to mechanical s
timulation of the tumor by the gravid uterus. Review of published case
reports since 1980 reveals that a pheochromocytoma during pregnancy m
ay be diagnosed in an extra-adrenal location relatively more commonly
compared to non-pregnant patients. Established criteria exist for the
adequacy of alpha- and beta-adrenergic blockade for the management of
pheochromocytoma in the non-pregnant patient. We discuss how these cri
teria apply to pregnant patients with pheochromocytoma, and suggest po
ssible modifications to the criteria.