Lingual Calcinosis circumscripta in a captive sitatunga

Calcinosis circumscripta (CC) was found in a 10-yr-old female sitatunga (Bo vidae; Tragelaphus spekei). At necropsy, there were two white coalescing no dules (3 x 5 x 2 cm, 2 x 2 x 1.5 cm) on the ventral side of the tongue. The cut surface of the nodules had multiple, well-circumscribed loculi with ch alky appearance and gritty consistency, separated by thin strands of connec tive tissue. Histologically, the nodules contained multiple loculi of vario us sizes and shapes, which consisted of amorphous material that was pale ba sophilic with H&E stain, surrounded by fibrous connective tissue. Around di e loculi were numerous foreign body giant cells and epithelioid macrophages ; occasional. lymphocyte aggregations also were seen. The amorphous materia l was positive for PAS and von Kossa's stain. Calcinosis circumscripta is r are in the Bovidae.