AN EFFICIENT SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANTIBIOTICS VIA REDUCTIVE CYCLIZATION

Authors
KAMAL A REDDY BSN REDDY BSP
Citation
A. Kamal et al., AN EFFICIENT SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANTIBIOTICS VIA REDUCTIVE CYCLIZATION, Bioorganic & medicinal chemistry letters, 7(14), 1997, pp. 1825-1828
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
14
Year of publication
1997
Pages
1825 - 1828
Database
ISI
SICI code
0960-894X(1997)7:14<1825:AESOPA>2.0.ZU;2-C
Abstract
A new and convenient one-pot synthesis of pyrrolo[2,1-c][1,4]benzodiaz epine (PBD) ring system has been achieved by a reductive cyclization e mploying N,N-dimethylhydrazine and FeCl3.6H(2)O in good yields. (C) 19 97 Elsevier Science Ltd.