Value of fine-needle aspiration cytology of parotid gland masses

Objective: To evaluate the usefulness and accuracy of fine-needle aspiratio n cytology (FNAC) in the diagnosis of parotid gland masses. Study Design: R etrospective chart review of patients undergoing FNAC. Methods: Between Jan uary 1990 and December 1998, 410 parotid glands were resected at the Depart ment of Otorhinolaryngology-Head and Neck Surgery at the University of Bern e, Inselpital (Berne, Switzerland). Included in the study were 228 cases wi th preoperative FNAC. In a retrospective study the results of FNAC were ana lyzed and compared with the corresponding histopathological diagnosis. Resu lts: Histological evaluation revealed 65 malignant tumors and 163 benign le sions (150 neoplasms and 13 nonneoplastic lesions). The cytological finding s were nondiagnostic in 13 (5.7%), true-negative in 146 (64%), true-positiv e in 39 (17%), false-negative in 22 (9.8%) and false-positive in 8 (4.5%) c ases in detecting malignant tumors. Nineteen of 39 (49%) malignant tumors ( true-positive) and 123 of 146 (84%) benign lesions (true-negative) were cla ssified accurately. The accuracy, sensitivity, and specificity were 86%, 64 %, and 95% respectively. Conclusions. Fine-needle aspiration cytology is a valuable adjunct to preoperative assessment of parotid masses. Preoperative recognition of malignant tumors may help prepare both the surgeon and pati ent for an appropriate surgical procedure.