IDENTIFICATION OF HUMAN MONOAMINE-OXIDASE (MAO)A AND (MAO)B GENE PROMOTERS

Authors
SHIH JC ZHU QS GRIMSBY J CHEN K
Citation
Jc. Shih et al., IDENTIFICATION OF HUMAN MONOAMINE-OXIDASE (MAO)A AND (MAO)B GENE PROMOTERS, Journal of neural transmission. Supplementum, (41), 1994, pp. 27-33
Citations number
11
Categorie Soggetti
Neurosciences
Journal title
Journal of neural transmission. Supplementum → ACNP
ISSN journal
03036995
Issue
41
Year of publication
1994
Pages
27 - 33
Database
ISI
SICI code
0303-6995(1994):41<27:IOHM(A>2.0.ZU;2-B
Abstract
The promoter of human monoamine oxidase (MAO) A and B genes have been identified. The core promoter region of MAO A is comprised of two 90bp repeats each of which contains two Sp1 elements and lacks a TATA box. The MAO B core promoter region contains two sets of overlapping Sp1 s ites which flank a CACCC element all upstream of a TATA box. The diffe rent organization of the MAO A and B promoters may underlie their diff erent cell and tissue specific expression.