Although the treatment of colloid cysts remains controversial, high viscosi
ty and small volume are poor prognostic indicators for successful burr hole
aspiration and cortical incision via craniotomy may be associated with pos
toperative epilepsy. The anterior transcallosal approach provides a direct
and adequate pathway to the lateral ventricles, where the foramen of Monro
serves as a natural entrance into the anterior third ventricle, especially
when the foramen is dilated by a lesion. When the midsuperior portion of th
e IIIrd ventricle cannot be reached, the interforniceal or the subchoroidal
exposures have been advocated. Stereotactic techniques contribute to a min
imal invasive approach and reduce morbidity. Nine patients harbouring anter
ior third ventricular cysts (seven colloids and two intrinsic craniopharyng
iomas) underwent anterior transcallosal microsurgical excision assisted by
an interactive infrared-based image guided system (EasyGuide, Neuro, Philip
s). There were 4 men and 5 women ranging in age from 15 to 42 years (mean 2
8.5). Transcallosal transforaminal (5 cases) or interforniceal (4 cases) ap
proaches allowed total excision in eight patients and subtotal in one. Post
operative morbidity included a case of transient hemiparesis and a case of
transient short-term memory disturbances; both resolved in the first months
. Mortality was zero. Particular advantages of the method were accurate tra
jectory and position of callosotomy incision determination, visualisation a
nd avoidance of superior saggital sinus, retraction of bridging veins and t
he often variable pericallosal arteries, spatial orientation within the ven
tricular system, and identification of the periventricular anatomical struc
tures.