Hyperbaric oxygen therapy for mitomycin C-induced scleral necrosis

Intraoperative or postoperative use of mitomycin C is one of the treatment options to reduce the recurrence of pterygia. Scleral necrosis, a potential ly blinding complication after mitomycin C use, has been among great concer n in ophthalmic practice. A patient is presented in whom scleral necrosis d eveloped 20 days after a pterygiectomy with bare sclera technique was perfo rmed, followed by the application of 0.4 mg/mL of topical mitomycin C eye d rops for 3 weeks. After conjunctival flap failures the patient was treated with hyperbaric oxygen therapy. The sclera revascularized and returned to n ear normal thickness after 24 sessions of hyperbaric oxygen therapy. This c ase demonstrates that it is an effective, novel treatment.