Development of acyclovir-resistant herpes simplex virus early during the treatment of herpes neonatorum

Authors
Levin, MJ Weinberg, A Leary, JJ Sarisky, RT
Citation
Mj. Levin et al., Development of acyclovir-resistant herpes simplex virus early during the treatment of herpes neonatorum, PEDIAT INF, 20(11), 2001, pp. 1094-1097
Citations number
12
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
PEDIATRIC INFECTIOUS DISEASE JOURNAL
ISSN journal
08913668 → ACNP
Volume
20
Issue
11
Year of publication
2001
Pages
1094 - 1097
Database
ISI
SICI code
0891-3668(200111)20:11<1094:DOAHSV>2.0.ZU;2-#
Abstract
Genotypic analysis of herpes simplex virus (HSV) DNA extracted from clinica l specimens from a case of fatal disseminated neonatal HSV demonstrated tha t an infant developed an acyclovir-resistant HSV containing a mutation in t he HSV thymidine kinase gene during the first seven days of acyclovir thera py.