Interference is frequently observed during bimanual movements if the two ha
nds perform nonsymmetric actions. We examined the source of bimanual interf
erence in two experiments in which we compared conditions involving symmetr
ic movements with conditions in which the movements were of different ampli
tudes or different directions. The target movements were cued either symbol
ically by letters or directly by the onset of the target locations. With sy
mbolic cues, reaction times were longer when the movements of the two hands
were not symmetric. With direct cues, reaction times it-ere the same for s
ymmetric and nonsymmetric movements. These results indicate that directly c
ued actions can be programmed in parallel for the two hands. Our results ch
allenge the hypothesis that the cost to initiate nonsymmetric movements is
due to spatial interference in a motor-programming stage. Rather the cost a
ppears to he caused by stimulus identification, response-selection processe
s connected to the processing of symbolic cues, or both.