Lymphatic tumor emboli of perirenal fat in patient with nephrotic syndromereceiving renal biopsy, ultimately revealed gastric adenocarcinoma with membranous glomerulonephritis

The association of malignancy with nephrotic syndrome and renal histopathol ogic abnormalities is well documented. Paraneoplastic proteinuria caused by membranous glomerulonephritis usually is made simultaneously with the diag nosis of a malignant tumor, or the two conditions are diagnosed within a ye ar of each other. We reported a patient who presented with nephrotic. syndr ome initially. Incidentally, in kidney specimens, pathologic findings showe d perirenal fatty tissue with malignancy tumor emboli in lymphatics. Therea fter, gastric adenocarcinoma was diagnosed by gastrointestinal panendoscopy with gastric biopsy under impression of malignancy associated with glomeru lonephritis. Patient died of complications of malignancy-related disseminat ed intravascular coagulation without chemotherapy after confirming diagnosi s was made three months later.