Endoscopic surgery of the sphenoid sinus can present the operator with a co
nsiderable challenge. The relationship of the sphenoid sinuses, in particul
ar on the lateral wall, to the carotid artery, optic nerve, as well as the
other anatomic structures, is of utmost importance. Surgical complications
can occur because of a lack of orientation during dissection. To avoid the
complications or lessen, somehow, the rate of complications, some described
the technique consisting of the opening of the sphenoid sinus ostium media
lly. Me studied 69 axial high resolution computed tomography (HRCT) of temp
oral bones to reveal the relationship of sphenoid sinus to the vital struct
ures and to get some measurements in the sphenoid sinus. The lateral distan
ce from the sphenoid ostium revealed that the lateral distance was about th
e distance between both ostea. We consider that in selected cases the disse
ction might be carried out laterally from the sphenoid ostium for safe enla
rgement of the ostium and approaching the sinus.