The Russian gene pool: Gene geography of erythrocytic gene markers (ACP1, PGM1, ESD, GLO1, and 6-PGD)

Citation
Ev. Balanovskaya et al., The Russian gene pool: Gene geography of erythrocytic gene markers (ACP1, PGM1, ESD, GLO1, and 6-PGD), RUSS J GEN, 37(8), 2001, pp. 951-963
Citations number
15
Categorie Soggetti
Molecular Biology & Genetics
Journal title
RUSSIAN JOURNAL OF GENETICS
ISSN journal
10227954 → ACNP
Volume
37
Issue
8
Year of publication
2001
Pages
951 - 963
Database
ISI
SICI code
1022-7954(200108)37:8<951:TRGPGG>2.0.ZU;2-Y
Abstract
The study continues the series of works on the Russian gene pool. Gene geog raphic analysis of five erythrocytic gene markers best studied in the Russi an population (ACP1, PGM1, ESD, GLO1, and 6-PGD) has been performed. Gene-g eographic electronic maps have been constructed for 13 alleles of these loc i and their correlations with geographic latitude and longitude. For all ma ps, statistical characteristics are presented, including the variation rang e and mean gene frequencies, partial and multiple correlations with latitud e and longitude, and parameters of heterozygosity and interpopulation diver sity. The maps of eight alleles (ACP1*A, ACP1*C, PGM1*2+, PGM1*2-, PGM1*1-, ESD*1, GLO1*1, and PGD*C) are shown and analyzed in detail. The genetic re lief and structural elements of the maps are compared with the ecumenical t rends, main variation patterns of these genes in northern Eurasia, and gene tic characteristics of the indigenous populations of the Urals and Europe.