The Russian gene pool: Frequencies of genetic markers

Citation
Va. Spitsyn et al., The Russian gene pool: Frequencies of genetic markers, RUSS J GEN, 37(3), 2001, pp. 302-314
Citations number
34
Categorie Soggetti
Molecular Biology & Genetics
Journal title
RUSSIAN JOURNAL OF GENETICS
ISSN journal
10227954 → ACNP
Volume
37
Issue
3
Year of publication
2001
Pages
302 - 314
Database
ISI
SICI code
1022-7954(200103)37:3<302:TRGPFO>2.0.ZU;2-E
Abstract
Frequency distribution of several genetic markers was studied in ethnic Rus sians from the Moscow, Bryansk, Ryazan', Kostroma, Novgorod, Arkhangel'sk, and Sverdlovsk oblasts and Udmurtiya. Systems AB0, RH, HP, TF, GC, PI, C'3, ACP1, PGM1, ESD, GLO1, 6PGD, and AKA,ere analyzed in most samples. New dat a on informative polymorphic genetic loci showed that the Russian gene pool mostly displays Caucasoid features. Some data on polymorphism of nuclear g enome loci are presented. In addition, Y-chromosomal short tandem repeats ( STRs) DYS19, DYS390, and DYCAII were analyzed in the Russian samples. STRs of the chromosome are particularly valuable for elucidating ethnogenetic pr ocesses in Eastern Europe. Frequency distributions of the Y-chromosomal mar kers in Russians were intermediate between those of West European populatio ns and eastern Finno-Ugric ethnoses of the Volga region. A marked longitudi nal gradient was revealed for frequencies of several molecular markers.