A radiation map of the short arm of porcine chromosome 2

Citation
Ev. Ivanova et al., A radiation map of the short arm of porcine chromosome 2, RUSS J GEN, 37(2), 2001, pp. 168-174
Citations number
25
Categorie Soggetti
Molecular Biology & Genetics
Journal title
RUSSIAN JOURNAL OF GENETICS
ISSN journal
10227954 → ACNP
Volume
37
Issue
2
Year of publication
2001
Pages
168 - 174
Database
ISI
SICI code
1022-7954(200102)37:2<168:ARMOTS>2.0.ZU;2-N
Abstract
In recent years, maps of mammalian genomes have been acquiring increasingly higher resolution. Integration of maps of different types has become possi ble. As a tool in integrating maps of mammalian genomes of different types, high-resolution mapping with radiation-induced hybrids (RH) is used. Here, we present an RH6000 map of the short arm of porcine chromosome 2. The map contains 15 microsatellites and five genes (for parathyroid hormone, lacta te dehydrogenase A, myogenic factor, follicle-stimulating hormone beta, and calpain 1). The RH panel was obtained on the basis of a hybrid cell line b earing the single porcine chromosome 2 against the background of mink chrom osomes. The mean frequency of preserving markers examined in the panel was 18.3%. Integration of four genes in the panel and a comparison of gene orde r in homeologous regions of human and porcine chromosomes are presented.