A printable glucose sensor was obtained by immobilisation of glucose oxidas
e onto the surface of poly(pyrrole)-coated latex spheres, which were mixed
with a conducting ink. The obtained hybrid material was able to amperometri
cally detect glucose under aerobic as well as anaerobic conditions, without
the use of electron mediators. Since all of the steps involved in the prep
aration of this latex-poly(pyrrole)based ink are performed in solution, in-
expensive mass production will be possible. A possible mechanism for this s
ensor is proposed based on the direct communication between the enzyme and
the conducting polymer under anaerobic conditions. (C) 2001 Elsevier Scienc
e B.V. All rights reserved.