3-acyl-2-(N-cyanoimino)oxazolidine derivative, a new asymmetric acylating agent for racemic secondary alkyl amines

Authors
Maezaki, N Furusawa, A Uchida, S Tanaka, T
Citation
N. Maezaki et al., 3-acyl-2-(N-cyanoimino)oxazolidine derivative, a new asymmetric acylating agent for racemic secondary alkyl amines, TETRAHEDRON, 57(45), 2001, pp. 9309-9315
Citations number
37
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
45
Year of publication
2001
Pages
9309 - 9315
Database
ISI
SICI code
0040-4020(20011105)57:45<9309:3DANAA>2.0.ZU;2-Z
Abstract
A 3-acyl-2-(N-cyanoimino)oxazolidine derivative was found to serve as an en antioselective acylating agent for sec-alkyl amines. These reagents differe ntiate the enantiomers of 1-phenylethylamine derivatives up to 85% ee, and the recovered chiral auxiliary is reusable. (C) 2001 Elsevier Science Ltd. All rights reserved.