A convenient synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine using Sharpless asymmetric aminohydroxylation

Authors
Kim, IH Kirk, KL
Citation
Ih. Kim et Kl. Kirk, A convenient synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine using Sharpless asymmetric aminohydroxylation, TETRAHEDR L, 42(48), 2001, pp. 8401-8403
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
48
Year of publication
2001
Pages
8401 - 8403
Database
ISI
SICI code
0040-4039(20011126)42:48<8401:ACSO2A>2.0.ZU;2-A
Abstract
Ring-fluorinated beta -hydroxy alpha -amino methyl esters 3b,c were synthes ized enantio selectively using Sharpless asymmetric amino hydroxylation. Th ese were converted to 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyph enyl)serine 1b,c using our previously published procedure. (C) 2001 Elsevie r Science Ltd. All rights reserved.