H-phosphonylphosphonate triethylester: the first member of a novel family of stable bisphosphorylated compounds; its short synthesis and reactivity with aldehydes

Authors
Bisseret, P Eustache, J
Citation
P. Bisseret et J. Eustache, H-phosphonylphosphonate triethylester: the first member of a novel family of stable bisphosphorylated compounds; its short synthesis and reactivity with aldehydes, TETRAHEDR L, 42(48), 2001, pp. 8451-8453
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
48
Year of publication
2001
Pages
8451 - 8453
Database
ISI
SICI code
0040-4039(20011126)42:48<8451:HTTFMO>2.0.ZU;2-C
Abstract
A short preparation of the first member (1) of the novel H-phosphonylphosph onate family is described. Its reaction with aldehydes provides a straightf orward access to the hitherto almost unprecedented class of alpha -hydroxyp hosphinylphosphonates 3 of potential value in particular in medicinal chemi stry. (C) 2001 Elsevier Science Ltd. All rights reserved.