A cycloaddition strategy for the synthesis of thiirane-containing glycomimetics

Authors
Avalos, M Babiano, R Cintas, P Clemente, FR Gordillo, R Hursthouse, MB Jimenez, JL Light, ME Palacios, JC
Citation
M. Avalos et al., A cycloaddition strategy for the synthesis of thiirane-containing glycomimetics, TETRAHEDR-A, 12(16), 2001, pp. 2265-2268
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
16
Year of publication
2001
Pages
2265 - 2268
Database
ISI
SICI code
0957-4166(20010913)12:16<2265:ACSFTS>2.0.ZU;2-E
Abstract
This manuscript describes a one-pot. selective synthesis of optically activ e thiiranes by [3+2] cycloaddition of mesoionic dipoles with sugar aldehyde s. Overall, the result is the formation of monosaccharide mimetics that dis play numerous functional groups for molecular recognition. (C) 2001 Elsevie r Science Ltd. All rights reserved.