Prune belly syndrome and congenital renal neoplasma

Background: High end sonography allows the prenatal localization of the kid neys and the corresponding urine drainage system as early as 10 - 13 weeks of gestation. In mid second trimester, the voiding and filling of the urina ry bladder can be demonstrated by ultrasound. Obstructions are the most com mon abnormalities of the urogenital tract. Though less frequent in incidenc e, more complex sequences of anomalies such as Prune Belly Syndrome or Mega cystis-Microcolon-Intestinal-Hypoperistalsis-Syndrome (MMIHS) can also be d etected in early gestational age. Materials and methods: Pathogenesis, prenatal diagnosis, pre- and postnatal treatment options and prognosis are discussed. Results and discussion: The same risk-adapted procedures aimed to protect t he fetal urinary excretory function known in the therapeutic regimen of obs tructive uropathy are available as treatment options. These range from non- invasive ultrasound for diagnosis and surveillance to needle procedures or even endoscopic interventions. Another rare entity of renal abnormalities a re congenital neoplasm's - megaloblastic nephroma, nephroblastoma and neuro blastoma. Conclusion: Prognosis and obstetrical management are to be determined indiv idually for each patient.