The cost of HIV/AIDS care was measured in Belgium in 1996. This paper is co
ncerned with direct costs (formal and informal care). This is a prospective
study, stratified by CDC-disease stage. A societal point of view was chose
n. Eighty-two sequential patients agreed to join the study during outpatien
t visits. Data on service use and costs were obtained through a care-cost d
iary kept over three months. Half of the patients (41) returned a completed
diary, which reduced the sample size considerably. Additional billing data
were obtained from different sources and by calculating the time spent for
certain services. In stage A (asymptomatic HIV), the mean ( +/-SD) annual
total direct costs are US$2,373 (2,079), rising to US$8,401 (7,520) in stag
e B (symptomatic HIV) and ending up at US$27,373 (22,087) in stage C (full
blown AIDS). A difference in balance of costs at different stages of diseas
e was observed. The principal cost of outpatient pharmaca in HIV patients i
s overtaken by the cost of hospitalization in AIDS patients. The cost of in
formal care is considerable (40% of the total cost) from stage B onwards. H
ealth care use and costs increase with severity of illness.