Extraction spectrophotometric determination of lidocaine using flow injection analysis

Authors
Nemcova, I Rychlovsky, P Tomankova, V Zivanovic, L
Citation
I. Nemcova et al., Extraction spectrophotometric determination of lidocaine using flow injection analysis, ANAL LETTER, 34(14), 2001, pp. 2457-2464
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL LETTERS
ISSN journal
00032719 → ACNP
Volume
34
Issue
14
Year of publication
2001
Pages
2457 - 2464
Database
ISI
SICI code
0003-2719(2001)34:14<2457:ESDOLU>2.0.ZU;2-5
Abstract
A new flow-through method (flow injection analysis, FIA) for the lidocaine assay, using extraction of ion - associate with bromocresol green, was prop osed. The optimum reaction and flow-through conditions (reagent concentrati ons, pH, flow rates of reagents, injected volume of sample, length of react ion and extraction coil, total flow rate through the separator, withdrawal rate of organic phase) were found. The Lambert-Beer's law is obeyed in the concentration range of 1.4-16.2 mug ml(-1).