Solid cystic papillary tumor of the pancreas.

Solid cystic papillary tumors of the pancreas are rare; they occur most com monly in young women. Despite their characteristic microscopic appearance, their immunophenotype is not specific. Their prognosis is excellent after c omplete surgical resection. The study aim was to report two cases in female patients who were 15 and 20 years old; the first tumor was discovered fort uitously and the second girl presented with abdominal pain and vomiting. Bo th tumors were encapsulated and located in the tail of the pancreas. The hi stological study showed the papillary architecture mixed with solid areas. Immunohistochemical staining was positive only for vimentin in one case and positive for cytokeratin, chromogranin, synaptophysin, neuron specific eno lase, vimentin and protein S100 in the second case. (C) 2001 Editions scien tifiques et medicales Elsevier SAS.