Nonculture prediction of Neisseria meningitidis susceptibility to penicillin

Authors
Antignac, A Alonso, JM Tara, MK
Citation
A. Antignac et al., Nonculture prediction of Neisseria meningitidis susceptibility to penicillin, ANTIM AG CH, 45(12), 2001, pp. 3625-3628
Citations number
29
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
12
Year of publication
2001
Pages
3625 - 3628
Database
ISI
SICI code
0066-4804(200112)45:12<3625:NPONMS>2.0.ZU;2-Q
Abstract
We developed a nonculture method to predict the susceptibility of Neisseria meningitidis to penicillin G. The penA gene was amplified and submitted to restriction fragment length polymorphism analysis. This approach was first validated with a collection of 75 meningococcal strains of known phenotype s. It was next successfully applied to 29 clinical samples.