Newer macrolides as empiric treatment for acute Q fever infection

Authors
Gikas, A Kofteridis, DP Manios, A Pediaditis, J Tselentis, Y
Citation
A. Gikas et al., Newer macrolides as empiric treatment for acute Q fever infection, ANTIM AG CH, 45(12), 2001, pp. 3644-3646
Citations number
18
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
12
Year of publication
2001
Pages
3644 - 3646
Database
ISI
SICI code
0066-4804(200112)45:12<3644:NMAETF>2.0.ZU;2-T
Abstract
The effectiveness of newer macrolides in acute Q fever for 113 patients was recorded. The mean times to defervescence were 2.9 days for doxycycline an d 3.3, 3.9, 3.9, and 6.4 days for clarithromycin, roxithromycin, erythromyc in, and beta -lactams, respectively (P < 0.01 for macrolides versus beta -l actams). We conclude that macrolides may be an adequate empirical antibioti c therapy for acute Q fever.