Benign myoepithelioma of the lung - A case report and review of the literature

This report describes a benign myoepithelioma of the lung that occurred in a 60-year-old woman. The patient had experienced hoarseness for 6 weeks, an d a computed tomographic scan showed a nodule of approximately 2 cm in diam eter at the peripheral portion of her right upper lung. Positron emission t omography showed no uptake of F-18 fluorodeoxyglucose in the nodule. Wedge biopsy of the lesion showed benign spindle cells arranged in a whorled patt ern. The cells were positive for both cytokeratin and smooth muscle actin, which corresponded to the presence of tonofilaments and myofilaments that w ere identified ultrastructurally. The features of the present case of benig n myoepithelioma that differ from features of previously reported benign an d malignant cases of myoepithelioma in the lung are discussed in the report .